Cargando…

DNA Polymerase Theta Plays a Critical Role in Pancreatic Cancer Development and Metastasis

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is one of the most deadly cancers worldwide. The occurrence of oncogenic KRAS mutations is considered a signature event in PDAC, leading to genomic instability. The aim of our study was to evaluate the impact of the oncogenic KRAS G12D mutation...

Descripción completa

Detalles Bibliográficos
Autores principales: Smolinska, Agnieszka, Singer, Kerstin, Golchert, Janine, Smyczynska, Urszula, Fendler, Wojciech, Sendler, Matthias, van den Brandt, Jens, Singer, Stephan, Homuth, Georg, Lerch, Markus M., Moskwa, Patryk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454495/
https://www.ncbi.nlm.nih.gov/pubmed/36077614
http://dx.doi.org/10.3390/cancers14174077