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DNA Polymerase Theta Plays a Critical Role in Pancreatic Cancer Development and Metastasis

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is one of the most deadly cancers worldwide. The occurrence of oncogenic KRAS mutations is considered a signature event in PDAC, leading to genomic instability. The aim of our study was to evaluate the impact of the oncogenic KRAS G12D mutation...

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Detalles Bibliográficos
Autores principales:	Smolinska, Agnieszka, Singer, Kerstin, Golchert, Janine, Smyczynska, Urszula, Fendler, Wojciech, Sendler, Matthias, van den Brandt, Jens, Singer, Stephan, Homuth, Georg, Lerch, Markus M., Moskwa, Patryk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454495/ https://www.ncbi.nlm.nih.gov/pubmed/36077614 http://dx.doi.org/10.3390/cancers14174077

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