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IL-10 Producing B Cells Protect against LPS-Induced Murine Preterm Birth by Promoting PD1- and ICOS-Expressing T Cells

B cells and in particular IL-10-secreting B cells emerge as important players in immune balance during pregnancy. We have recently revealed that CD19-deficient (CD19(−/−)), B cell-specific IL-10-deficient (BIL-10(−/−)) and B cell-deficient µMT pregnant mice are highly susceptible to LPS-induced pret...

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Detalles Bibliográficos
Autores principales: Busse, Mandy, Zenclussen, Ana Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454497/
https://www.ncbi.nlm.nih.gov/pubmed/36078100
http://dx.doi.org/10.3390/cells11172690