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Temsirolimus Enhances Anti-Cancer Immunity by Inducing Autophagy-Mediated Degradation of the Secretion of Small Extracellular Vesicle PD-L1

SIMPLE SUMMARY: Immune checkpoint blockade therapies (ICBT) have increasing importance in patient survival and prognosis because it enhances immune cell activation by inhibiting the binding of programmed death-ligand 1 (PD-L1) of tumor and programmed death-1 (PD-1) of T cells. However, tumor-derived...

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Detalles Bibliográficos
Autores principales: Park, Seong-Sik, Kim, Jong-In, Lee, Chan-Hyeong, Bae, Ju-Hyun, Park, Ju-Mi, Choe, Eun-Ji, Baek, Moon-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454510/
https://www.ncbi.nlm.nih.gov/pubmed/36077620
http://dx.doi.org/10.3390/cancers14174081