Whole-Exome Sequencing Identifies Pathogenic Germline Variants in Patients with Lynch-Like Syndrome

SIMPLE SUMMARY: A significant proportion of families with a clinical suggestion of Lynch syndrome and screened for the known MMR genes remain without a molecular diagnosis. These patients, who generally show a suggestive family pedigree or early-onset tumors with MMR deficiency and no detectable ger...

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Detalles Bibliográficos
Autores principales: dos Santos, Wellington, de Andrade, Edilene Santos, Garcia, Felipe Antonio de Oliveira, Campacci, Natália, Sábato, Cristina da Silva, Melendez, Matias Eliseo, Reis, Rui Manuel, Galvão, Henrique de Campos Reis, Palmero, Edenir Inez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454535/
https://www.ncbi.nlm.nih.gov/pubmed/36077770
http://dx.doi.org/10.3390/cancers14174233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454535/
https://www.ncbi.nlm.nih.gov/pubmed/36077770
http://dx.doi.org/10.3390/cancers14174233

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