Enhanced Cytotoxicity on Cancer Cells by Combinational Treatment of PARP Inhibitor and 5-Azadeoxycytidine Accompanying Distinct Transcriptional Profiles

SIMPLE SUMMARY: We investigated the effect of combinational use of PARP inhibitors on cytotoxicity of 5-aza-dC in human cancer cell lines. The combinational treatment of 5-aza-dC and PARP inhibitor PJ-34 exhibited a stronger cytotoxicity compared with their treatment alone in blood cancer HL-60, U93...

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Detalles Bibliográficos
Autores principales: Araki, Tomonori, Hamada, Kensuke, Myat, Aung Bhone, Ogino, Hideki, Hayashi, Kohei, Maeda, Miho, Tong, Ying, Murakami, Yasufumi, Nakao, Kazuhiko, Masutani, Mitsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454563/
https://www.ncbi.nlm.nih.gov/pubmed/36077707
http://dx.doi.org/10.3390/cancers14174171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454563/
https://www.ncbi.nlm.nih.gov/pubmed/36077707
http://dx.doi.org/10.3390/cancers14174171

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