Cargando…

PARP1: Liaison of Chromatin Remodeling and Transcription

SIMPLE SUMMARY: Poly(ADP-ribose) polymerase 1 (PARP1) is perhaps the most studied member of the PARP superfamily and participates in numerous cellular processes. PARP1 inhibitors have been approved as drugs to treat various cancers in clinics, based on its role in DNA repair. Yet, there is a growing...

Descripción completa

Detalles Bibliográficos
Autores principales: Zong, Wen, Gong, Yamin, Sun, Wenli, Li, Tangliang, Wang, Zhao-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454564/
https://www.ncbi.nlm.nih.gov/pubmed/36077699
http://dx.doi.org/10.3390/cancers14174162