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PARP1: Liaison of Chromatin Remodeling and Transcription
SIMPLE SUMMARY: Poly(ADP-ribose) polymerase 1 (PARP1) is perhaps the most studied member of the PARP superfamily and participates in numerous cellular processes. PARP1 inhibitors have been approved as drugs to treat various cancers in clinics, based on its role in DNA repair. Yet, there is a growing...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454564/ https://www.ncbi.nlm.nih.gov/pubmed/36077699 http://dx.doi.org/10.3390/cancers14174162 |