Physiological Mineralization during In Vitro Osteogenesis in a Biomimetic Spheroid Culture Model

Bone health-targeting drug development strategies still largely rely on inferior 2D in vitro screenings. We aimed at developing a scaffold-free progenitor cell-based 3D biomineralization model for more physiological high-throughput screenings. MC3T3-E1 pre-osteoblasts were cultured in α-MEM with 10%...

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Detalles Bibliográficos
Autores principales: Koblenzer, Maximilian, Weiler, Marek, Fragoulis, Athanassios, Rütten, Stephan, Pufe, Thomas, Jahr, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454617/
https://www.ncbi.nlm.nih.gov/pubmed/36078105
http://dx.doi.org/10.3390/cells11172702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454617/
https://www.ncbi.nlm.nih.gov/pubmed/36078105
http://dx.doi.org/10.3390/cells11172702

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