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Physiological Mineralization during In Vitro Osteogenesis in a Biomimetic Spheroid Culture Model
Bone health-targeting drug development strategies still largely rely on inferior 2D in vitro screenings. We aimed at developing a scaffold-free progenitor cell-based 3D biomineralization model for more physiological high-throughput screenings. MC3T3-E1 pre-osteoblasts were cultured in α-MEM with 10%...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454617/ https://www.ncbi.nlm.nih.gov/pubmed/36078105 http://dx.doi.org/10.3390/cells11172702 |