Prevalence of ARID1A Mutations in Cell-Free Circulating Tumor DNA in a Cohort of 71,301 Patients and Association with Driver Co-Alterations

SIMPLE SUMMARY: ARID1A abnormalities disturb gene coding processes and correlate with immunotherapy responsiveness. We report the first blood sample-based genomic sequencing of ARID1A in DNA shed from tumors into the circulation (known as cell-free DNA (cfDNA) from liquid biopsy). Altogether, of 62,...

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Detalles Bibliográficos
Autores principales: Kurzrock, Razelle, Aggarwal, Charu, Weipert, Caroline, Kiedrowski, Lesli, Riess, Jonathan, Lenz, Heinz-Josef, Gandara, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454642/
https://www.ncbi.nlm.nih.gov/pubmed/36077815
http://dx.doi.org/10.3390/cancers14174281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454642/
https://www.ncbi.nlm.nih.gov/pubmed/36077815
http://dx.doi.org/10.3390/cancers14174281

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