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TROP2 Represents a Negative Prognostic Factor in Colorectal Adenocarcinoma and Its Expression Is Associated with Features of Epithelial–Mesenchymal Transition and Invasiveness

SIMPLE SUMMARY: Colorectal cancer (CRC) is one of the most common cancers worldwide. While the systemic treatment of CRC is based on chemotherapy, subsequent therapeutic options are far less effective. Trophoblast cell surface antigen 2 (TROP2) is highly expressed in many carcinomas, including CRC,...

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Detalles Bibliográficos
Autores principales: Švec, Jiří, Šťastná, Monika, Janečková, Lucie, Hrčkulák, Dušan, Vojtěchová, Martina, Onhajzer, Jakub, Kříž, Vítězslav, Galušková, Kateřina, Šloncová, Eva, Kubovčiak, Jan, Pfeiferová, Lucie, Hrudka, Jan, Matěj, Radoslav, Waldauf, Petr, Havlůj, Lukáš, Kolář, Michal, Kořínek, Vladimír
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454662/
https://www.ncbi.nlm.nih.gov/pubmed/36077674
http://dx.doi.org/10.3390/cancers14174137