The Intranigral Infusion of Human-Alpha Synuclein Oligomers Induces a Cognitive Impairment in Rats Associated with Changes in Neuronal Firing and Neuroinflammation in the Anterior Cingulate Cortex

Parkinson’s disease (PD) is a complex pathology causing a plethora of non-motor symptoms besides classical motor impairments, including cognitive disturbances. Recent studies in the PD human brain have reported microgliosis in limbic and neocortical structures, suggesting a role for neuroinflammatio...

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Detalles Bibliográficos
Autores principales: Palmas, Maria Francesca, Etzi, Michela, Pisanu, Augusta, Camoglio, Chiara, Sagheddu, Claudia, Santoni, Michele, Manchinu, Maria Francesca, Pala, Mauro, Fusco, Giuliana, De Simone, Alfonso, Picci, Luca, Mulas, Giovanna, Spiga, Saturnino, Scherma, Maria, Fadda, Paola, Pistis, Marco, Simola, Nicola, Carboni, Ezio, Carta, Anna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454687/
https://www.ncbi.nlm.nih.gov/pubmed/36078036
http://dx.doi.org/10.3390/cells11172628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454687/
https://www.ncbi.nlm.nih.gov/pubmed/36078036
http://dx.doi.org/10.3390/cells11172628

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