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The Intranigral Infusion of Human-Alpha Synuclein Oligomers Induces a Cognitive Impairment in Rats Associated with Changes in Neuronal Firing and Neuroinflammation in the Anterior Cingulate Cortex
Parkinson’s disease (PD) is a complex pathology causing a plethora of non-motor symptoms besides classical motor impairments, including cognitive disturbances. Recent studies in the PD human brain have reported microgliosis in limbic and neocortical structures, suggesting a role for neuroinflammatio...
Autores principales: | Palmas, Maria Francesca, Etzi, Michela, Pisanu, Augusta, Camoglio, Chiara, Sagheddu, Claudia, Santoni, Michele, Manchinu, Maria Francesca, Pala, Mauro, Fusco, Giuliana, De Simone, Alfonso, Picci, Luca, Mulas, Giovanna, Spiga, Saturnino, Scherma, Maria, Fadda, Paola, Pistis, Marco, Simola, Nicola, Carboni, Ezio, Carta, Anna R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454687/ https://www.ncbi.nlm.nih.gov/pubmed/36078036 http://dx.doi.org/10.3390/cells11172628 |
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