Inhibition of PGE2 in Subchondral Bone Attenuates Osteoarthritis

Aberrant subchondral bone architecture is a crucial driver of the pathological progression of osteoarthritis, coupled with increased sensory innervation. The sensory PGE2/EP4 pathway is involved in the regulation of bone mass accrual by the induction of differentiation of mesenchymal stromal cells....

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Detalles Bibliográficos
Autores principales: Sun, Qi, Zhang, Yuanzhen, Ding, Yilan, Xie, Wenqing, Li, Hengzhen, Li, Shaohua, Li, Yusheng, Cai, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454853/
https://www.ncbi.nlm.nih.gov/pubmed/36078169
http://dx.doi.org/10.3390/cells11172760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454853/
https://www.ncbi.nlm.nih.gov/pubmed/36078169
http://dx.doi.org/10.3390/cells11172760

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