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Determining the Potential of DNA Damage Response (DDR) Inhibitors in Cervical Cancer Therapy

SIMPLE SUMMARY: Cervical cancer (CC) is the fourth most common cause of cancer deaths in women. For patients where surgery is not an option, they are treated with cisplatin and radiotherapy (RT) that acts by damaging DNA. However, response is poor, and cisplatin causes kidney injury. The DNA damage...

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Detalles Bibliográficos
Autores principales: Saha, Santu, Rundle, Stuart, Kotsopoulos, Ioannis C., Begbie, Jacob, Howarth, Rachel, Pappworth, Isabel Y., Mukhopadhyay, Asima, Kucukmetin, Ali, Marchbank, Kevin J., Curtin, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454916/
https://www.ncbi.nlm.nih.gov/pubmed/36077823
http://dx.doi.org/10.3390/cancers14174288