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Genomic and Epigenomic Characterization of Tumor Organoid Models

SIMPLE SUMMARY: The patient-derived organoid (PDO) model is a versatile and dynamic tool for investigating individual genomic and epigenomic properties of cancer. PDOs preserve key (epi-)genomic features and maintain physiological and pathological characteristics, resembling patient tumor specimens....

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Detalles Bibliográficos
Autores principales: Nam, Chehyun, Ziman, Benjamin, Sheth, Megha, Zhao, Hua, Lin, De-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454968/
https://www.ncbi.nlm.nih.gov/pubmed/36077628
http://dx.doi.org/10.3390/cancers14174090