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Targeting the Unwindosome by Mebendazole Is a Vulnerability of Chemoresistant Hepatoblastoma

SIMPLE SUMMARY: Hepatoblastoma patients with tumors that do not respond to preoperative chemotherapy often experience incomplete surgical resection and thus poor outcomes. By analyzing the gene expression data of chemoresistant and responsive tumors using sophisticated drug prediction software we id...

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Detalles Bibliográficos
Autores principales: Li, Qian, Demir, Salih, Del Río-Álvarez, Álvaro, Maxwell, Rebecca, Wagner, Alexandra, Carrillo-Reixach, Juan, Armengol, Carolina, Vokuhl, Christian, Häberle, Beate, von Schweinitz, Dietrich, Schmid, Irene, Cairo, Stefano, Kappler, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454988/
https://www.ncbi.nlm.nih.gov/pubmed/36077733
http://dx.doi.org/10.3390/cancers14174196