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Targeting the Unwindosome by Mebendazole Is a Vulnerability of Chemoresistant Hepatoblastoma
SIMPLE SUMMARY: Hepatoblastoma patients with tumors that do not respond to preoperative chemotherapy often experience incomplete surgical resection and thus poor outcomes. By analyzing the gene expression data of chemoresistant and responsive tumors using sophisticated drug prediction software we id...
Autores principales: | Li, Qian, Demir, Salih, Del Río-Álvarez, Álvaro, Maxwell, Rebecca, Wagner, Alexandra, Carrillo-Reixach, Juan, Armengol, Carolina, Vokuhl, Christian, Häberle, Beate, von Schweinitz, Dietrich, Schmid, Irene, Cairo, Stefano, Kappler, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454988/ https://www.ncbi.nlm.nih.gov/pubmed/36077733 http://dx.doi.org/10.3390/cancers14174196 |
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