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Double Deletion of PI3K and PTEN Modifies Lens Postnatal Growth and Homeostasis

We have previously shown that the conditional deletion of either the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K), or its opposing phosphatase, phosphatase and tensin homolog (PTEN), had distinct effects on lens growth and homeostasis. The deletion of p110α reduced the levels of p...

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Detalles Bibliográficos
Autores principales: Sellitto, Caterina, Li, Leping, White, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455000/
https://www.ncbi.nlm.nih.gov/pubmed/36078116
http://dx.doi.org/10.3390/cells11172708