Alpinetin Suppresses Effects of TGF-β1 on Stimulating the Production and Organization of Fibrotic Markers in Human Primary Dermal Fibroblasts

Overgrowths of dermal fibroblasts and myofibroblast phenoconversion in response to TGF-β stimulation are the hallmarks of skin fibrosis. Constitutive activation of dermal fibroblasts by TGF-β induces the excessive production of extracellular matrix as well as certain key intracellular proteins which...

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Detalles Bibliográficos
Autores principales: Wikan, Nitwara, Potikanond, Saranyapin, Nimlamool, Wutigri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455016/
https://www.ncbi.nlm.nih.gov/pubmed/36078140
http://dx.doi.org/10.3390/cells11172731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455016/
https://www.ncbi.nlm.nih.gov/pubmed/36078140
http://dx.doi.org/10.3390/cells11172731

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