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Phenotypic and Genetic Evidence for a More Prominent Role of Blood Glucose than Cholesterol in Atherosclerosis of Hyperlipidemic Mice

Hyperlipidemia and type 2 diabetes (T2D) are major risk factors for atherosclerosis. Apoe-deficient (Apoe(−/−)) mice on certain genetic backgrounds develop hyperlipidemia, atherosclerosis, and T2D when fed a Western diet. Here, we sought to dissect phenotypic and genetic relationships of blood lipid...

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Detalles Bibliográficos
Autores principales: Abramson, Ashley M., Shi, Lisa J., Lee, Rebecca N., Chen, Mei-Hua, Shi, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455034/
https://www.ncbi.nlm.nih.gov/pubmed/36078077
http://dx.doi.org/10.3390/cells11172669