The Central Domain of MCPH1 Controls Development of the Cerebral Cortex and Gonads in Mice

MCPH1 is the first gene identified to be responsible for the human autosomal recessive disorder primary microcephaly (MCPH). Mutations in the N-terminal and central domains of MCPH1 are strongly associated with microcephaly in human patients. A recent study showed that the central domain of MCPH1, w...

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Detalles Bibliográficos
Autores principales: Wang, Yaru, Zong, Wen, Sun, Wenli, Chen, Chengyan, Wang, Zhao-Qi, Li, Tangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455054/
https://www.ncbi.nlm.nih.gov/pubmed/36078123
http://dx.doi.org/10.3390/cells11172715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455054/
https://www.ncbi.nlm.nih.gov/pubmed/36078123
http://dx.doi.org/10.3390/cells11172715

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