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Distinct and Dynamic Transcriptome Adaptations of iPSC-Generated Astrocytes after Cytokine Stimulation

Astrocytes (ACs) do not only play a role in normal neurogenesis and brain homeostasis, but also in inflammatory and neurodevelopmental disorders. We studied here the different patterns of inflammatory activation triggered by cytokines in human induced pluripotent stem cell (iPSC)-derived ACs. An opt...

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Detalles Bibliográficos
Autores principales: Spreng, Anna-Sophie, Brüll, Markus, Leisner, Heidrun, Suciu, Ilinca, Leist, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455058/
https://www.ncbi.nlm.nih.gov/pubmed/36078052
http://dx.doi.org/10.3390/cells11172644