Mineralocorticoid Receptor Antagonists Mitigate Mitral Regurgitation-Induced Myocardial Dysfunction

Mitral regurgitation (MR), the disruption of the mitral valve, contributes to heart failure (HF). Under conditions of volume overload, excess mineralocorticoids promote cardiac fibrosis. The mineralocorticoid receptor antagonist spironolactone is a potassium-sparing diuretic and a guideline-recommen...

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Detalles Bibliográficos
Autores principales: Chang, Wei-Ting, Lin, Yu-Wen, Chen, Chin-Yu, Chen, Zhih-Cherng, Shih, Jhih-Yuan, Wu, Chia-Ching, Luo, Chwan-Yau, Liu, Ping-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455158/
https://www.ncbi.nlm.nih.gov/pubmed/36078158
http://dx.doi.org/10.3390/cells11172750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455158/
https://www.ncbi.nlm.nih.gov/pubmed/36078158
http://dx.doi.org/10.3390/cells11172750

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