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Mineralocorticoid Receptor Antagonists Mitigate Mitral Regurgitation-Induced Myocardial Dysfunction
Mitral regurgitation (MR), the disruption of the mitral valve, contributes to heart failure (HF). Under conditions of volume overload, excess mineralocorticoids promote cardiac fibrosis. The mineralocorticoid receptor antagonist spironolactone is a potassium-sparing diuretic and a guideline-recommen...
Autores principales: | Chang, Wei-Ting, Lin, Yu-Wen, Chen, Chin-Yu, Chen, Zhih-Cherng, Shih, Jhih-Yuan, Wu, Chia-Ching, Luo, Chwan-Yau, Liu, Ping-Yen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455158/ https://www.ncbi.nlm.nih.gov/pubmed/36078158 http://dx.doi.org/10.3390/cells11172750 |
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