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Patient-Derived Pancreatic Cancer Cells Induce C2C12 Myotube Atrophy by Releasing Hsp70 and Hsp90

Pancreatic cancer (PC) patients are highly prone to cachexia, a lethal wasting syndrome featuring muscle wasting with an undefined etiology. Recent data indicate that certain murine cancer cells induce muscle wasting by releasing Hsp70 and Hsp90 through extracellular vesicles (EVs) to activate p38β...

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Detalles Bibliográficos
Autores principales: Wu, Hong-Yu, Trevino, Jose G., Fang, Bing-Liang, Riner, Andrea N., Vudatha, Vignesh, Zhang, Guo-Hua, Li, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455268/
https://www.ncbi.nlm.nih.gov/pubmed/36078164
http://dx.doi.org/10.3390/cells11172756