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SGLT2 Inhibitor Empagliflozin Modulates Ion Channels in Adult Zebrafish Heart

Empagliflozin, an inhibitor of sodium-glucose co-transporter 2 (iSGLT2), improves cardiovascular outcomes in patients with and without diabetes and possesses an antiarrhythmic activity. However, the mechanisms of these protective effects have not been fully elucidated. This study aimed to explore th...

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Detalles Bibliográficos
Autores principales: Karpushev, Alexey V., Mikhailova, Valeria B., Klimenko, Ekaterina S., Kulikov, Alexander N., Ivkin, Dmitry Yu., Kaschina, Elena, Okovityi, Sergey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455557/
https://www.ncbi.nlm.nih.gov/pubmed/36076956
http://dx.doi.org/10.3390/ijms23179559