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Polysialic Acid Sustains the Hypoxia-Induced Migration and Undifferentiated State of Human Glioblastoma Cells

Gliomas are the most common primary malignant brain tumors. Glioblastoma, IDH-wildtype (GBM, CNS WHO grade 4) is the most aggressive form of glioma and is characterized by extensive hypoxic areas that strongly correlate with tumor malignancy. Hypoxia promotes several processes, including stemness, m...

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Detalles Bibliográficos
Autores principales: Rosa, Paolo, Scibetta, Sofia, Pepe, Giuseppe, Mangino, Giorgio, Capocci, Luca, Moons, Sam J., Boltje, Thomas J., Fazi, Francesco, Petrozza, Vincenzo, Di Pardo, Alba, Maglione, Vittorio, Calogero, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455737/
https://www.ncbi.nlm.nih.gov/pubmed/36076963
http://dx.doi.org/10.3390/ijms23179563