MicroRNA Let-7a, -7e and -133a Attenuate Hypoxia-Induced Atrial Fibrosis via Targeting Collagen Expression and the JNK Pathway in HL1 Cardiomyocytes

Fibrosis is a hallmark of atrial structural remodeling. The main aim of this study was to investigate the role of micro-ribonucleic acids (miRNAs) in the modulation of fibrotic molecular mechanisms in response to hypoxic conditions, which may mediate atrial fibrosis. Under a condition of hypoxia ind...

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Detalles Bibliográficos
Autores principales: Lo, Chien-Hsien, Li, Li-Ching, Yang, Shun-Fa, Tsai, Chin-Feng, Chuang, Yao-Tsung, Chu, Hsiao-Ju, Ueng, Kwo-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455749/
https://www.ncbi.nlm.nih.gov/pubmed/36077031
http://dx.doi.org/10.3390/ijms23179636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455749/
https://www.ncbi.nlm.nih.gov/pubmed/36077031
http://dx.doi.org/10.3390/ijms23179636

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