Discovery of 4-nitro-3-phenylisoxazole derivatives as potent antibacterial agents derived from the studies of [3 + 2] cycloaddition

Polysubstituted phenylisoxazoles were designed and synthesized to discover new antibacterial agents via [3 + 2] cycloaddition. Thirty-five compounds with a phenylisoxazole scaffold were characterized by NMR, HRMS, and X-ray techniques. After being evaluated against Xanthomonas oryzae (Xoo), Pseudomo...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Long, Zhiwu, Yan, Longjia, Liu, Li, Yang, Lan, Le, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455768/
https://www.ncbi.nlm.nih.gov/pubmed/36199305
http://dx.doi.org/10.1039/d2ra05009a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455768/
https://www.ncbi.nlm.nih.gov/pubmed/36199305
http://dx.doi.org/10.1039/d2ra05009a

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