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Dock10 Regulates Cardiac Function under Neurohormonal Stress

Dedicator of cytokinesis 10 (Dock10) is a guanine nucleotide exchange factor for Cdc42 and Rac1 that regulates the JNK (c-Jun N-terminal kinase) and p38 MAPK (mitogen-activated protein kinase) signaling cascades. In this study, we characterized the roles of Dock10 in the myocardium. In vitro: we abl...

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Detalles Bibliográficos
Autores principales: Segal, Liad, Etzion, Sharon, Elyagon, Sigal, Shahar, Moran, Klapper-Goldstein, Hadar, Levitas, Aviva, Kapiloff, Michael S., Parvari, Ruti, Etzion, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455810/
https://www.ncbi.nlm.nih.gov/pubmed/36077014
http://dx.doi.org/10.3390/ijms23179616