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Succinate and inosine coordinate innate immune response to bacterial infection

Macrophages restrict bacterial infection partly by stimulating phagocytosis and partly by stimulating release of cytokines and complement components. Here, we treat macrophages with LPS and a bacterial pathogen, and demonstrate that expression of cytokine IL-1β and bacterial phagocytosis increase to...

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Detalles Bibliográficos
Autores principales: Jiang, Ming, Chen, Zhuang-gui, Li, Hui, Zhang, Tian-tuo, Yang, Man-jun, Peng, Xuan-xian, Peng, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455851/
https://www.ncbi.nlm.nih.gov/pubmed/36026499
http://dx.doi.org/10.1371/journal.ppat.1010796