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RAFFT: Efficient prediction of RNA folding pathways using the fast Fourier transform

We propose a novel heuristic to predict RNA secondary structure formation pathways that has two components: (i) a folding algorithm and (ii) a kinetic ansatz. This heuristic is inspired by the kinetic partitioning mechanism, by which molecules follow alternative folding pathways to their native stru...

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Detalles Bibliográficos
Autores principales: Opuu, Vaitea, Merleau, Nono S. C., Messow, Vincent, Smerlak, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455880/
https://www.ncbi.nlm.nih.gov/pubmed/36026505
http://dx.doi.org/10.1371/journal.pcbi.1010448