Downregulation of miR-99b-5p and Upregulation of Nuclear mTOR Cooperatively Promotes the Tumor Aggressiveness and Drug Resistance in African American Prostate Cancer

Mammalian target of rapamycin (mTOR) regulates various fundamental cellular events including cell proliferation, protein synthesis, metabolism, apoptosis, and autophagy. Tumor suppressive miR-99b-5p has been implicated in regulating PI3K/AKT/mTOR signaling in a variety of types of cancer. Our previo...

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Detalles Bibliográficos
Autores principales: Gujrati, Himali, Ha, Siyoung, Waseem, Mohammad, Wang, Bi-Dar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455949/
https://www.ncbi.nlm.nih.gov/pubmed/36077039
http://dx.doi.org/10.3390/ijms23179643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455949/
https://www.ncbi.nlm.nih.gov/pubmed/36077039
http://dx.doi.org/10.3390/ijms23179643

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