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Characterization of Vemurafenib-Resistant Melanoma Cell Lines Reveals Novel Hallmarks of Targeted Therapy Resistance

Regardless of the significant improvements in treatment of melanoma, the majority of patients develop resistance whose mechanisms are still not completely understood. Hence, we generated and characterized two melanoma-derived cell lines, primary WM793B and metastatic A375M, with acquired resistance...

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Detalles Bibliográficos
Autores principales: Radić, Martina, Vlašić, Ignacija, Jazvinšćak Jembrek, Maja, Horvat, Anđela, Tadijan, Ana, Sabol, Maja, Dužević, Marko, Herak Bosnar, Maja, Slade, Neda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455970/
https://www.ncbi.nlm.nih.gov/pubmed/36077308
http://dx.doi.org/10.3390/ijms23179910