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DNA Damage Induction Alters the Expression of Ubiquitin and SUMO Regulators in Preimplantation Stage Pig Embryos

DNA damage in early-stage embryos impacts development and is a risk factor for segregation of altered genomes. DNA damage response (DDR) encompasses a sophisticated network of proteins involved in sensing, signaling, and repairing damage. DDR is regulated by reversible post-translational modificatio...

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Detalles Bibliográficos
Autores principales: da Silva, Zigomar, Glanzner, Werner Giehl, Currin, Luke, de Macedo, Mariana Priotto, Gutierrez, Karina, Guay, Vanessa, Gonçalves, Paulo Bayard Dias, Bordignon, Vilceu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455980/
https://www.ncbi.nlm.nih.gov/pubmed/36077022
http://dx.doi.org/10.3390/ijms23179610