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Systemic Beta-Hydroxybutyrate Affects BDNF and Autophagy into the Retina of Diabetic Mice

Background: Diabetic retinopathy (DR) is a neurovascular disease, characterized by a deficiency of brain-derived neurotrophic factor (BDNF), a regulator of autophagy. Beta-hydroxybutyrate (BHB), previously reported as a protective agent in DR, has been associated with BDNF promotion. Here, we invest...

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Detalles Bibliográficos
Autores principales: Trotta, Maria Consiglia, Gesualdo, Carlo, Herman, Hildegard, Gharbia, Sami, Balta, Cornel, Lepre, Caterina Claudia, Russo, Marina, Itro, Annalisa, D’Amico, Giovanbattista, Peluso, Luisa, Panarese, Iacopo, Pieretti, Gorizio, Ferraro, Giuseppe, Simonelli, Francesca, D’Amico, Michele, Rossi, Settimio, Hermenean, Anca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455989/
https://www.ncbi.nlm.nih.gov/pubmed/36077579
http://dx.doi.org/10.3390/ijms231710184