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Albumin/Thiacalix[4]arene Nanoparticles as Potential Therapeutic Systems: Role of the Macrocycle for Stabilization of Monomeric Protein and Self-Assembly with Ciprofloxacin

The therapeutic application of serum albumin is determined by the relative content of the monomeric form compared to dimers, tetramers, hexamers, etc. In this paper, we propose and develop an approach to synthesize the cone stereoisomer of p-tert-butylthiacalix[4]arene with sulfobetaine fragments st...

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Detalles Bibliográficos
Autores principales: Yakimova, Luidmila, Kunafina, Aisylu, Mostovaya, Olga, Padnya, Pavel, Mukhametzyanov, Timur, Voloshina, Alexandra, Petrov, Konstantin, Boldyrev, Artur, Stoikov, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455997/
https://www.ncbi.nlm.nih.gov/pubmed/36077448
http://dx.doi.org/10.3390/ijms231710040