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Albumin/Thiacalix[4]arene Nanoparticles as Potential Therapeutic Systems: Role of the Macrocycle for Stabilization of Monomeric Protein and Self-Assembly with Ciprofloxacin
The therapeutic application of serum albumin is determined by the relative content of the monomeric form compared to dimers, tetramers, hexamers, etc. In this paper, we propose and develop an approach to synthesize the cone stereoisomer of p-tert-butylthiacalix[4]arene with sulfobetaine fragments st...
Autores principales: | Yakimova, Luidmila, Kunafina, Aisylu, Mostovaya, Olga, Padnya, Pavel, Mukhametzyanov, Timur, Voloshina, Alexandra, Petrov, Konstantin, Boldyrev, Artur, Stoikov, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455997/ https://www.ncbi.nlm.nih.gov/pubmed/36077448 http://dx.doi.org/10.3390/ijms231710040 |
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