Small RNA-Seq Reveals Similar miRNA Transcriptome in Children and Young Adults with T-ALL and Indicates miR-143-3p as Novel Candidate Tumor Suppressor in This Leukemia

We aimed to identify miRNAs and pathways specifically deregulated in adolescent and young adult (AYA) T-ALL patients. Small RNA-seq showed no major differences between AYA and pediatric T-ALL, but it revealed downregulation of miR-143-3p in T-ALL patients. Prediction algorithms identified several kn...

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Detalles Bibliográficos
Autores principales: Dawidowska, Małgorzata, Maćkowska-Maślak, Natalia, Drobna-Śledzińska, Monika, Kosmalska, Maria, Jaksik, Roman, Szymczak, Donata, Jarmuż-Szymczak, Małgorzata, Sadowska-Klasa, Alicja, Wojtaszewska, Marzena, Sędek, Łukasz, Wróbel, Tomasz, Zaucha, Jan Maciej, Szczepański, Tomasz, Lewandowski, Krzysztof, Giebel, Sebastian, Witt, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456032/
https://www.ncbi.nlm.nih.gov/pubmed/36077521
http://dx.doi.org/10.3390/ijms231710117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456032/
https://www.ncbi.nlm.nih.gov/pubmed/36077521
http://dx.doi.org/10.3390/ijms231710117

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