Pretreatment with Zonisamide Mitigates Oxaliplatin-Induced Toxicity in Rat DRG Neurons and DRG Neuron–Schwann Cell Co-Cultures

Oxaliplatin (OHP) is a platinum-based agent that can cause peripheral neuropathy, an adverse effect in which the dorsal root ganglion (DRG) neurons are targeted. Zonisamide has exhibited neuroprotective activities toward adult rat DRG neurons in vitro and therefore, we aimed to assess its potential...

Descripción completa

Detalles Bibliográficos
Autores principales: Takaku, Shizuka, Sango, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456039/
https://www.ncbi.nlm.nih.gov/pubmed/36077386
http://dx.doi.org/10.3390/ijms23179983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456039/
https://www.ncbi.nlm.nih.gov/pubmed/36077386
http://dx.doi.org/10.3390/ijms23179983

Ejemplares similares