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Reversal of High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Metformin Combined with PGG, an Inducer of Glycine N-Methyltransferase

Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver-related morbidities and mortality, and no effective drug treatment currently exists. We aimed to develop a novel treatment strategy to induce the expression of glycine N-methyltransferase (GNMT), which is an important enzyme regulati...

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Detalles Bibliográficos
Autores principales: Yang, Ming-Hui, Li, Wei-You, Wu, Ching-Fen, Lee, Yi-Ching, Chen, Allan Yi-Nan, Tyan, Yu-Chang, Chen, Yi-Ming Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456083/
https://www.ncbi.nlm.nih.gov/pubmed/36077467
http://dx.doi.org/10.3390/ijms231710072