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Metal Ion Periplasmic-Binding Protein YfeA of Glaesserella parasuis Induces the Secretion of Pro-Inflammatory Cytokines of Macrophages via MAPK and NF-κB Signaling through TLR2 and TLR4

The YfeA gene, belonging to the well-conserved ABC (ATP-binding cassette) transport system Yfe, encodes the substrate-binding subunit of the iron, zinc, and manganese transport system in bacteria. As a potential vaccine candidate in Glaesserella parasuis, the functional mechanisms of YfeA in the inf...

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Detalles Bibliográficos
Autores principales: Yang, Zhen, Tang, Xinwei, Wang, Kang, Dai, Ke, Chang, Yung-Fu, Du, Senyan, Zhao, Qin, Huang, Xiaobo, Wu, Rui, Yan, Qigui, Cao, Sanjie, Wen, Yiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456096/
https://www.ncbi.nlm.nih.gov/pubmed/36077023
http://dx.doi.org/10.3390/ijms23179627