PET Probes for Preclinical Imaging of GRPR-Positive Prostate Cancer: Comparative Preclinical Study of [(68)Ga]Ga-NODAGA-AMBA and [(44)Sc]Sc-NODAGA-AMBA

Gastrin-releasing peptide receptors (GRPR) are overexpressed in prostate cancer (PCa). Since bombesin analogue aminobenzoic-acid (AMBA) binds to GRPR with high affinity, scandium-44 conjugated AMBA is a promising radiotracer in the PET diagnostics of GRPR positive tumors. Herein, the GRPR specificit...

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Detalles Bibliográficos
Autores principales: Kálmán-Szabó, Ibolya, Szabó, Judit P., Arató, Viktória, Dénes, Noémi, Opposits, Gábor, Jószai, István, Kertész, István, Képes, Zita, Fekete, Anikó, Szikra, Dezső, Hajdu, István, Trencsényi, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456106/
https://www.ncbi.nlm.nih.gov/pubmed/36077458
http://dx.doi.org/10.3390/ijms231710061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456106/
https://www.ncbi.nlm.nih.gov/pubmed/36077458
http://dx.doi.org/10.3390/ijms231710061

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