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TNF-α Plus IL-1β Induces Opposite Regulation of Cx43 Hemichannels and Gap Junctions in Mesangial Cells through a RhoA/ROCK-Dependent Pathway

Connexin 43 (Cx43) is expressed in kidney tissue where it forms hemichannels and gap junction channels. However, the possible functional relationship between these membrane channels and their role in damaged renal cells remains unknown. Here, analysis of ethidium uptake and thiobarbituric acid react...

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Detalles Bibliográficos
Autores principales: Lucero, Claudia M., Marambio-Ruiz, Lucas, Balmazabal, Javiera, Prieto-Villalobos, Juan, León, Marcelo, Fernández, Paola, Orellana, Juan A., Velarde, Victoria, Sáez, Juan C., Gómez, Gonzalo I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456118/
https://www.ncbi.nlm.nih.gov/pubmed/36077498
http://dx.doi.org/10.3390/ijms231710097