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Tuning of Liver Sieve: The Interplay between Actin and Myosin Regulatory Light Chain Regulates Fenestration Size and Number in Murine Liver Sinusoidal Endothelial Cells

Liver sinusoidal endothelial cells (LSECs) facilitate the efficient transport of macromolecules and solutes between the blood and hepatocytes. The efficiency of this transport is realized via transcellular nanopores, called fenestrations. The mean fenestration size is 140 ± 20 nm, with the range fro...

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Detalles Bibliográficos
Autores principales: Zapotoczny, Bartlomiej, Szafranska, Karolina, Lekka, Malgorzata, Ahluwalia, Balpreet Singh, McCourt, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456121/
https://www.ncbi.nlm.nih.gov/pubmed/36077249
http://dx.doi.org/10.3390/ijms23179850