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Reorganization of the Landscape of Translated mRNAs in NSUN2-Deficient Cells and Specific Features of NSUN2 Target mRNAs

The RNA cytosine C5 methyltransferase NSUN2 has a variety of RNA substrates and plays an important role in mRNA metabolism. NSUN2 binds to specific sequences enriched in exosomal mRNAs, suggesting its possible involvement in the sorting of mRNAs into exosomes. We applied the photoactivatable.4-thiou...

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Detalles Bibliográficos
Autores principales: Kossinova, Olga A., Gopanenko, Alexander V., Babaylova, Elena S., Tupikin, Alexey E., Kabilov, Marsel R., Malygin, Alexey A., Karpova, Galina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456143/
https://www.ncbi.nlm.nih.gov/pubmed/36077143
http://dx.doi.org/10.3390/ijms23179740