From Double-Strand Break Recognition to Cell-Cycle Checkpoint Activation: High Content and Resolution Image Cytometry Unmasks 53BP1 Multiple Roles in DNA Damage Response and p53 Action

53BP1 protein has been isolated in-vitro as a putative p53 interactor. From the discovery of its engagement in the DNA-Damage Response (DDR), its role in sustaining the activity of the p53-regulated transcriptional program has been frequently under-evaluated, even in the case of a specific response...

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Detalles Bibliográficos
Autores principales: Furia, Laura, Pelicci, Simone, Scanarini, Mirco, Pelicci, Pier Giuseppe, Faretta, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456172/
https://www.ncbi.nlm.nih.gov/pubmed/36077590
http://dx.doi.org/10.3390/ijms231710193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456172/
https://www.ncbi.nlm.nih.gov/pubmed/36077590
http://dx.doi.org/10.3390/ijms231710193

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