Co-Formulation of Amphiphilic Cationic and Anionic Cyclodextrins Forming Nanoparticles for siRNA Delivery in the Treatment of Acute Myeloid Leukaemia

Non-viral delivery of therapeutic nucleic acids (NA), including siRNA, has potential in the treatment of diseases with high unmet clinical needs such as acute myeloid leukaemia (AML). While cationic biomaterials are frequently used to complex the nucleic acids into nanoparticles, attenuation of char...

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Detalles Bibliográficos
Autores principales: Kont, Ayse, Mendonça, Monique C. P., Cronin, Michael F., Cahill, Mary R., O’Driscoll, Caitriona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456197/
https://www.ncbi.nlm.nih.gov/pubmed/36077202
http://dx.doi.org/10.3390/ijms23179791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456197/
https://www.ncbi.nlm.nih.gov/pubmed/36077202
http://dx.doi.org/10.3390/ijms23179791

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