Tankyrase Inhibition Attenuates Cardiac Dilatation and Dysfunction in Ischemic Heart Failure

Hyperactive poly(ADP-ribose) polymerases (PARP) promote ischemic heart failure (IHF) after myocardial infarction (MI). However, the role of tankyrases (TNKSs), members of the PARP family, in pathogenesis of IHF remains unknown. We investigated the expression and activation of TNKSs in myocardium of...

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Detalles Bibliográficos
Autores principales: Wang, Hong, Segersvärd, Heli, Siren, Juuso, Perttunen, Sanni, Immonen, Katariina, Kosonen, Riikka, Chen, Yu-Chia, Tolva, Johanna, Laivuori, Mirjami, Mäyränpää, Mikko I., Kovanen, Petri T., Sinisalo, Juha, Laine, Mika, Tikkanen, Ilkka, Lakkisto, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456217/
https://www.ncbi.nlm.nih.gov/pubmed/36077457
http://dx.doi.org/10.3390/ijms231710059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456217/
https://www.ncbi.nlm.nih.gov/pubmed/36077457
http://dx.doi.org/10.3390/ijms231710059

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